Engram
Engramclinical

Research billing automation for clinical trial finance teams

Automate Medicare Coverage Analysis, Epic charge classification, and budget reconciliation. Reduce MCA turnaround from days to hours. Recover unbilled sponsor charges. Full decision traceability for every determination.

SOC 2 Type II
HIPAA Compliant
21 CFR Part 11
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The problem

Your billing team is underwater.

Protocols stack up. MCA backlogs grow. Sponsor invoices wait weeks. Your analysts toggle between PDFs, spreadsheets, and Epic all day. There has to be a better way.

01
$2.1B
Annual leakage

US research sites lose billions in unbilled sponsor charges, missed holdbacks, and coding errors.

02
5–10 days
MCA turnaround

Your billing analysts spend hours cross-referencing NCD 310.1 against each protocol. Studies wait.

03
34%
Misclassified

Charges billed to wrong payer. SOC vs research distinctions unclear. Audit findings pile up.

04
67%
Amendments missed

Protocol changes affect budgets and MCAs. Without tracking, downstream billing is wrong from day one.

05
Audit TrailCompliance

Every decision documented. Exportable rationale for MAC audits.

04
Coverage EngineMedicare Coverage

Applies NCD logic and all applicable Medicare coverage guidelines to each determination.

03
Document ParsingProtocol + Budget + CTA

Extract procedures, visits, costs from your source documents.

02
Epic IntegrationCharge capture

Ingest extracts. Classify invoiceability. Map to timepoints.

01
Security LayerHIPAA + SOC 2

BAA-ready. SSO/SAML. Role-based access for your team.

How it works

End-to-end billing automation

Upload your protocol, budget, and CTA. Engram parses them, applies NCD logic and all applicable Medicare coverage guidelines, and produces coverage determinations with documented rationale. Feed it Epic extracts and get classified, invoiceable charges back.

Your analysts review and approve. The system learns your institutional preferences over time.

See the modules
12
Research sites
Top 20 US academic medical centers
1,000+
MCAs completed
With full audit documentation
$31M
Revenue recovered
Unbilled charges identified

"We went from a 10-day MCA backlog to same-day turnaround. My analysts now spend time on exceptions, not routine determinations."

Director of Research Billing
NCI-Designated Cancer Center

"The audit came and went. Every determination had a documented rationale. No callouts on our coverage analysis designations for the first time in years."

Clinical Research Finance Manager
Top 10 US Academic Medical Center

Why Engram

Built for research billing

Not a general-purpose AI tool. Purpose-built for Medicare coverage analysis, Epic charge classification, and sponsor invoicing at academic medical centers.

01

Reads your documents

Upload protocol PDFs, Excel budgets, Word CTAs. Engram extracts visits, procedures, and costs automatically. No manual data entry.

PDF, XLSX, DOCX
supported
02

Documents every decision

Every coverage determination includes the NCD section cited, the protocol page referenced, and the logic applied. Ready for MAC review.

100%
traceable
03

Knows billing rules

Built on NCD 310.1, LCD rules, and CMS guidance. Not a chatbot—specialized models trained on actual coverage determinations.

98.4%
accuracy
04

Your team stays in control

AI classifies and recommends. Your analysts review and approve. Configurable thresholds determine what needs human review.

Human
oversight

Security & Compliance

Ready for your IT review

Your compliance team will ask questions. We have answers. Security questionnaire, SOC 2 report, BAA, and architecture documentation available on request.

DeploymentCloud or on-premise
SSOSAML 2.0 / Okta / Azure AD
SupportDedicated CSM + 4-hour SLA
TrainingIncluded for your team
HIPAA
BAA included. PHI stays in your control.
SOC 2
Type II attested. Report available on request.
21 CFR Part 11
Audit trails and electronic signatures.
AES-256
Encrypted in transit and at rest.

Get started

Run a pilot on your actual protocols.

Send us 3-5 protocols. We'll run full MCA analysis and show you what Engram finds—misclassified charges, budget gaps, unbilled sponsor items. No commitment required.

30-minute setup callResults in 48 hours